Welcome to the Evelyn F. McKnight Brain Institute
at the University of Miami

Neuroplasticity of the Brain & Physical Exercise: Keeping a Sharp Mind

Neuroplasticity is the ability of the brain to develop new neural pathways or connections between brain cells or neurons. Most neurodegenerative diseases such as Alzheimer’s or Parkinson’s as well as mild cognitive impairment, are accompanied by a loss of brain plasticity.

We are grateful for the support of the McKnight Brain Research Foundation that established our Institute to investigate and treat age-related cognitive decline. Our basic and clinical research cores support multi-disciplinary research across scientific disciplines, and our educational programs foster the growth of scientists and clinicians at all levels of training and of the community at large. Through our collaborative and translational programs across McKnight Brain Institutes at the University of Alabama, the University of Arizona, and the University of Florida we hope to pioneer approaches that accelerate treatments and practical interventions to address the needs of our aging population.

Ralph L Sacco, MD, MS Executive Director


Tatjana Rundek, MD, PhD Scientific Director

Learn more about the McKnight Brain Institute


Xiaoyan Sun, MD, PhD,
Education Director


Bonnie Levin, PhD,
Cognitive Core Director

Stacy S. Merritt, MA,
Research and Adminstration Director

Susan Fox-Rosellini, Executive Director of Development & Marketing, Neurology Department