Sang H. Lee

Sang H. Lee

Sang Lee has been a member of Dr. Noam Alperin’s MR research group for more than 20 years by participating in many important projects including implementation of the pulsatility based method for segmentation (PUBS) of lumen conducting non steady flow. He helped to develop MR based method for measurements of intracranial compliance and pressure, and he has built experiences and knowledge in hydro- and hemo-dynamics of the cranio-spinal system. Currently, Sang Lee is a member of the Advanced Image Processing Lab (AIPL) and Physiologic Imaging and Modeling Lab (PIML) in the Department of Radiology, University of Miami. Sang Lee is proficient with brain segmentation/parcellation software packages such as FreeSurfer, FMRIB Software Library and ASHS (Automatic Segmentation of Hippocampal Subfields).

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Noam Alperin, PhD

Noam Alperin came to the University of Miami in May 2009 from the University of Illinois at Chicago. He obtained his Graduate Degree from the University of Chicago’s Medical Physics program. Dr. Alperin’s research focuses on blood and CSF flow dynamics using flow sensitive MRI techniques. A primary aim of the research is to provide noninvasively, important physiologic parameters among which are cerebral blood perfusion and intracranial pressure. These parameters play impotent role in a wide range of neurological problems, including hydrocephalous and stroke. Since joining the University of Miami, Dr. Alperin’ Advance Image Processing laboratory is working closely with the Evelyn F. McKnight Center for Age Related Memory Loss, using different MRI modalities to characterize and quantify morphologic and physiologic changes in the brain associated with aging as well as the coupling between age related brain tissue volume loss and cerebral blood flow decrease.

Michelle Marrero, MD

Dr. Michelle Marrero grew up in San Juan, Puerto Rico. She graduated with honors from the University of Puerto Rico – Mayagüez Campus, with a Bachelors Degree in Biology. She got her Medical Degree with Honors from the University of Puerto Rico School of Medicine and did her Residency in Neurology at the University of Miami, Jackson Memorial Hospital.

Dr. Marrero is passionate about brain health and the integrative treatment of the person as a whole, taking into consideration the physical, emotional, nutritional, spiritual and environmental influences that contribute to health and brain wellness. As a Neurologist, she treats brain disorders such as Epilepsy, Stroke, Traumatic Brain Injury, Movement Disorders and Headaches among others. She is currently pursuing a fellowship in Cognitive and Behavioral Neurology at the University of Miami where she will study and conduct research on memory disorders and the impact of neurological damage and disease upon behavior, memory and cognition.

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Hong Jiang, M.D., Ph.D.

Hong Jiang, M.D. Ph.D. is an Assistant Professor of Neurology and Ophthalmology at the University of Miami, Miller School of Medicine. She earned her undergraduate medical degree from Zhejiang University in Hangzhou, China. She received her Ph.D. at the University of Hong Kong in Hong Kong, China. Dr. Jiang completed her Neurology residency training at Jackson Memorial Hospital/University of Miami, and her Neuro-ophthalmology fellowship at Bascom Palmer Eye Institute, University of Miami.

As a neuro-ophthalmologist at the Bascom Palmer Eye Institute, Dr. Jiang specializes in the diagnosis and treatment of various neuro-ophthalmologic disorders, such as vision loss due to brain tumor or dementia, optic neuritis and double vision. In the Department of Neurology, Dr. Jiang provides expertise in the evaluation and treatment of various neurologic diseases such as memory disorders, headaches, spine diseases and Multiple Sclerosis.

Dr. Jiang’s research interest is to study the ocular microvascular dysfunction in ocular and central nervous system diseases, such as dry eye, dementia and multiple sclerosis. She has multiple publications in ocular microvascular function studies. She is interested in studying the vascular pathway in the pathogenesis of Alzheimer’s disease. With support from both the McKnight Brain Institute and North American Neuro-Ophthalmology society (NANOS), she and her team at Bascom Palmer Eye Institute recently found that decreased retinal microvascular network density and blood flow volume in patients with Alzheimer’s disease compared to normal controls.

Dr. Jiang is a member of the North American Neuro-Ophthalmology Society (NANOS), the American Academy of Neurology (AAN), the American Academy of Ophthalmology (AAO) and the Association for Research in Vision and

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Joyce Gomes-Osman, P.T., Ph.D.

Dr. Joyce Gomes-Osman is a physical therapist and a neuroscientist. After completing her physical therapy degree in her native country of Brazil, she obtained her Ph.D. at the University of Miami Miller School of Medicine, and a postdoctoral fellowship at Harvard Medical School. As a rehabilitation neuroscientist, Dr. Gomes-Osman is driven to answer questions that can impact people’s ability to live more functional and independent lives. She has published many research studies focused on figuring out ways to make rehabilitation therapies more effective for instance, by combining it with nerve stimulation and non-invasive brain stimulation. In addition to her interest in physical health, her work in recent years has focused on better understanding how we can promote brain health for individuals who are aging. This interest in brain health has stemmed both from scientific curiosity, and from experiencing the reality behind the statistics, witnessing memory deficits as a family member. Dr. Gomes-Osman is an Assistant Professor at the Departments of Physical Therapy and Neurology at University of Miami, and maintains her affiliation with the Berenson-Allen Center for Non-Invasive Brain Stimulation at Beth Israel Deaconess Medical Center, Harvard Medical School. She is also a KL2 scholar from the Clinical and Translational Science Institute at UM. She divides her time between working in the Laboratory, and teaching neurophysiology and non-invasive brain stimulation. She finds great joy in mentoring the next generation of physical therapy clinicians and clinician-scientists, whether it be in the classroom, or carrying out studies to disentangle the complex relationships between physical exercise, brain health and postural control in older adults and individuals with various neurological conditions. On her free time, she enjoys spending time with her family and is passionate about cooking and growing tropical plants, including exotic orchids.

David Della-Morte, MD, PhD

David Della-Morte received his MD and PhD degrees in Clinical Physiopathology and Experimental Medicine at University of Naples “Federico II”, Naples, Italy. Since 2005, Dr. Della-Morte has been working at the Department of Neurology, University of Miami, and was trained as a Postdoc in Neuroscience at the Cerebrovascular Disease Research Center. He is currently a Research Associate Professor of Neurology there. He is also an Associate Professor of Internal Medicine, University of Tor Vergata, and the Director of the Geriatric Unit at Tor Vergata Hospital, Rome, Italy, and Co-Director of IC-LOC (Interdisciplinary Center for Advanced Studies on Lab-on-Chip and Organ-on-Chip Applications) at the same university. Dr. Della-Morte is involved in both basic and clinical science in the field of aging, metabolic, cardiovascular and cerebrovascular disease. His current research focus is to clarify the pathological pathways linking metabolic diseases with cognitive impairment typical of elderly patients and with genetic disorders, such as Huntington Disease. Moreover, he is currently working on analyzing the role of particular antioxidants enzymes, such as peroxiredoxins, serum/glucocorticoid regulated kinase 1 (SGK-1), and sirtuins, in delay senescence processes. Dr. Della-Morte is also involved in genetics studies aimed to identify genetic factors influencing the development of vascular aging and cognition.

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Kunjan R. Dave, PhD

Dr. Dave received his PhD in Biochemistry in 2000 from the M. S. University of Baroda, India. During his PhD training he worked on several research projects including secondary complications of diabetes, Alzheimer’s disease and drug toxicity among others. From 1999 to 2000 Dr. Dave served at the Zandu Pharmaceutical Works, Mumbai, India, as a Biochemist, where he participated in a drug development program. The goal of Dr. Dave’s current research is to study potential signaling pathways responsible for neuronal death in neurodegenerative diseases, especially cerebral ischemia. Investigation of intracellular signaling pathways may lead to the development of novel therapies for patients with neurodegenerative diseases and stroke. Dr. Dave’s research also investigates the effect of cerebral ischemia on cognitive and motor functions in young and old rats.

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Noam Alperin, PhD

alperin-195x260Professor of Radiology and Biomedical Engineering
Physiologic Imaging and Modeling Lab
Advance Image Processing Lab
University of Miami Miller School of Medicine
Professional Art Center
1150 NW 14th Street, Suite 713
Miami, FL 33136
Email: Nalperin@med.miami.edu

Noam Alperin came to the University of Miami in May 2009 from the University of Illinois at Chicago. He obtained his Graduate Degree from the University of Chicago’s Medical Physics program. Dr. Alperin’s research focuses on blood and CSF flow dynamics using flow sensitive MRI techniques. A primary aim of the research is to provide noninvasively, important physiologic parameters among which are cerebral blood perfusion and intracranial pressure. These parameters play impotent role in a wide range of neurological problems, including hydrocephalous and stroke. Since joining the University of Miami, Dr. Alperin’ Advance Image Processing laboratory is working closely with the Evelyn F. McKnight Center for Age Related Memory Loss, using different MRI modalities to characterize and quantify morphologic and physiologic changes in the brain associated with aging as well as the coupling between age related brain tissue volume loss and cerebral blood flow decrease.

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Kunjan R. Dave, PhD

dave-195x260Research Associate Professor
Department of Neurology
1420 NW 9th Ave,
NRB/ 204,
Miami, FL 33136
Phone: 305-243-3590
Email: KDave@med.miami.edu

Dr. Dave received his PhD in Biochemistry in 2000 from the M. S. University of Baroda, India. During his PhD training he worked on several research projects including secondary complications of diabetes, Alzheimer’s disease and drug toxicity among others. From 1999 to 2000 Dr. Dave served at the Zandu Pharmaceutical Works, Mumbai, India, as a Biochemist, where he participated in a drug development program. The goal of Dr. Dave’s current research is to study potential signaling pathways responsible for neuronal death in neurodegenerative diseases, especially cerebral ischemia. Investigation of intracellular signaling pathways may lead to the development of novel therapies for patients with neurodegenerative diseases and stroke. Dr. Dave’s research also investigates the effect of cerebral ischemia on cognitive and motor functions in young and old rats.

David Della-Morte, MD, PhD

Associate Professor
Department of Neurology
University of Miami, Miller School of Medicine
1120 NW 14th Street, Suite 1363
Miami, FL 33136
Phone: 305-243-4790
Fax: 305-243-7081
Email: ddellamorte@med.miami.edu

David Della-Morte received his MD degree and his PhD in Clinical Physiopathology and Experimental Medicine at University of Naples “Federico II”, Naples, Italy. Since 2005, Dr. Della Morte has been working at the Department of Neurology, University of Miami, and was trained as a Postdoc in Neuroscience at the Cerebrovascular Disease Research Center. Currently, he is a Research Associate Professor of Neurology at the same University. Since 2013, he has also been appointed Assistant Professor of Internal Medicine, Department of Systems Medicine, University of Tor Vergata, Rome, Italy and a collaborator with the IRCCS San Raffaele Pisana Rome, Italy since 2010. Dr. Della-Morte is involved in both basic and clinical science in the field of aging, metabolic, cardiovascular and cerebrovascular disease. His current research focus is to clarify the pathological pathways linking metabolic diseases with cognitive impairment typical of elderly patients and with genetic disorders, such as Huntington Disease. Moreover, he is currently working on analyzing the role of particular antioxidants enzymes, such as peroxiredoxins, serum/glucocorticoid regulated kinase 1 (SGK-1), and sirtuins, in delay senescence processes. Dr. Della-Morte is also involved in genetics studies aimed to identify genetic factors influencing the development of vascular aging and cognition.

 

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